Metallo-β-Lactamase Production byPseudomonas otitidis: a Species-Related Trait
نویسندگان
چکیده
منابع مشابه
Biochemical characterization of the POM-1 metallo-β-lactamase from Pseudomonas otitidis.
The POM-1 metallo-β-lactamase is a subclass B3 resident enzyme produced by Pseudomonas otitidis, a pathogen causing otic infections. The enzyme was overproduced in Escherichia coli BL21(DE3), purified by chromatography, and subjected to structural and functional analysis. The purified POM-1 is a tetrameric enzyme of broad substrate specificity with higher catalytic activities with penicillins a...
متن کاملNew Delhi Metallo-β-Lactamase, Ontario, Canada
To the Editor: The New Delhi metallo-β-lactamase (NDM-1) was fi rst characterized in 2009 from Kleb-siella pneumoniae and Escherichia coli isolated from a patient in Sweden who had received medical care in New Delhi, India (1). Further studies have shown broad dissemination of this β-lactamase gene (bla NDM-1) in India, Pakistan, Bangladesh, and the United Kingdom (2). Additional isolates have ...
متن کاملPrevalence of Extended-Spectrum and Metallo β-Lactamase Production in AmpC β-Lactamase Producing Pseudomonas aeruginosa Isolates From Burns
BACKGROUND Pseudomonas aeruginosa is one of the most common causes of nosocomial infections. Resistance of P. aeruginosa to β-lactam antibiotics may be the result of acquired resistance through mutation and over production of various antibiotic inactivating enzymes. This research aimed to determine the prevalence of extended-spectrum β-lactamases (ESBL) and metallo β-lactamase (MBL) production ...
متن کاملA subclass B3 metallo-β-lactamase found in Pseudomonas alcaligenes.
addition, both PVL-positive spa t034 isolates contained genes associated with hlb-converting phages, namely sak, chp and scn. Although we did not have detailed epidemiological information on all nine patients, it is notable that three of the patients in this study had recent exposure to pigs. In other settings, isolation of CC398 MRSA has been strongly associated with exposure to livestock, inc...
متن کاملprevalence of extended-spectrum and metallo β-lactamase production in ampc β-lactamase producing pseudomonas aeruginosa isolates from burns
conclusions a high prevalence of multiple β-lactamase production was observed among the ampc producers (60%), of which the majority co-produced ampc and mbl. the current study results showed correlation between β-lactamase production and the presence of antibiotic resistance genes in the isolates. results all isolates were multidrug resistant. ampc, esbl and mbl production were observed in 35 (...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2010
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01062-10